Centro de Estudios de Metabolismo Fosfocálcico (CEMFOC)

  1. Rittweger J, Goosey-Tolfrey VL, Cointry GR, Ferretti JL. Structural analysis of the human tibia in men with spinal cord injury by tomographic (pQCT) serial scans. Bone 2010; 47:511-518.
  2. Feldman S, Capozza RF, Mortarino PA, Reina PS, Ferretti JL, Rittweger J, Cointry GR. Site and Sex Effects on Tibia Structure in Distance Runners and Untrained People. Med Sci Sports Exerc 2012; 44(8):1580-1588.
  3. Capozza RF, Rittweger J, Reina PS, Mortarino P, Nocciolino LM, Feldman S, Ferretti JL, Cointry GR. pQCT-assessed relationships between diaphyseal design and cortical bone mass density in the tibiae of healthy sedentary and trained men and women. Journal of Musculoskeletal & Neuronal Interactions (Berlín) 2013; 13(2):195-205.
  4. Capozza RF, Mondelo N, Reina PS, Nocciolino L, Meta M, Ferretti JL, Cointry GR. Mineralization- and remodeling-unrelated effects of high doses of olpadronate (dimethyl-pamidronate) on the pre- and post-yield properties of rat cortical bone. Journal of Musculoskeletal & Neuronal Interactions (Berlín) 2013; 13(2):185-94.
  5. Cointry GR, Reina PS, Nocciolino LM, Feldman S, Rittweger J, Ferretti JL, Capozza RF. Relative mechanical impact and diagnostic value of the indicators of bone tissue and design quality employed in their calculation in healthy men and pre- and post-menopausal women. Journal of Musculoskeletal & Neuronal Interactions (Berlín) 2014; 14(1):29-40.
  6. Reina P, Cointry GR, Nocciolino L, Feldman S, Ferretti JL, Rittweger J, Capozza RF. Analysis of the independent power of age-related, anthropometric and mechanical factors as determinants of the structure of radius and tibia in normal adults. A pQCT study. J Musculoskelet Neuronal Interact 2015; 15(1):10-22.
  7. Cointry GR, Nocciolino L, Ireland A, Hall NM, Kriechbaumer A, Ferretti JL, Rittweger J, Capozza RF. Structural differences in cortical shell properties between upper and lower human fibula as described by pQCT serial scans. A biomechanical interpretation. Bone 2016; 90:185-94.
  8. Ireland A, Capozza RF, Cointry GR, Nocciolino L, Ferretti JL, Rittweger J. Meagre effects of disuse on the human fibula are not explained by bone size or geometry. Osteoporos Int 2017; 28(2):633-641.
  9. Rittweger J, Ireland A, Lüscher S, Nocciolino LM, Pilot N, Pisani L, Cointry GR, Ferretti JL, Capozza RF. Fibula: The forgotten bone – May it provide some insight on a wider scope for bone mechanostat control? Current Osteoporosis Reports (Suiza) 2018; 16(6):775-778.
  10. Denova-Gutiérrez E, Clark P, Capozza RF, Nocciolino LM, Ferretti JL, Velázquez-Cruz R, Rivera B, Cointry GR, Salmerón J. Differences in the relation between bone mineral content and lean body mass according to gender and reproductive status by age ranges. J Bone Miner Metab 2019; 37(4):749-758.
  11. Vera MC, Ferretti JL, Abdala V, Cointry GR. Biomechanical Properties of Anuran Long Bones: Correlations with Locomotor Modes and Habitat Use. Journal of Anatomy, en prensa.

Instituto de Diagnóstico e Investigaciones Metabólicas (IDIM)

  1. Zanchetta MB, Abdala R, Massari F, Rey Paula, Spivacow R, Miechi L, Longobardi V, Brun LR. Postmenopausal women with sarcopenia have higher prevalence of falls and vertebral fractures. Medicina (BsAs), en prensa 2020.
  2. McClung MR, Brown JP, Diez-Perez A, Resch H, Caminis J, Meisner P, Bolognese MA, Goemaere S, Bone HG, Zanchetta JR, Maddox J, Bray S, Grauer A. Effects of 24 Months of Treatment With Romosozumab Followed by 12 Months of Denosumab or Placebo in Postmenopausal Women With Low Bone Mineral Density: A Randomized, Double-Blind, Phase 2, Parallel Group Study. J Bone Miner Res. 2018
  3. Bilezikian JP, Hattersley G, Fitzpatrick LA, Harris AG, Shevroja E, Banks K, Leder BZ, Zanchetta JR, Hans D. Abaloparatide-SC improves trabecular microarchitecture as assessed by trabecular bone score (TBS): a 24-week randomized clinical trial. Osteoporos Int 2018; 29(2):323-328.
  4. Zanchetta MB, Costa AF, Longobardi V, Mazure R, Silveira F, Temprano MP, Vázquez H, Bogado C, Niveloni SI, Smecuol E, Moreno ML, González A, Mauriño E, Zanchetta JR, Bai JC. Improved Bone Microarchitecture in Patients With Celiac Disease After 3 Years on a Gluten-Free Diet. Clin Gastroenterol Hepatol 2018; 16(5):774-775.
  5. Zanchetta MB, Boailchuk J, Massari F, Silveira F, Bogado C, Zanchetta JR. Significant bone loss after stopping long-term denosumab treatment: a post FREEDOM study. Osteoporos Int. 2018; 29(1):41-47.
  6. Zanchetta MB, Longobardi V, Costa F, Longarini G, Mazure RM, Moreno ML, Vázquez H, Silveira F, Niveloni S, Smecuol E, de la Paz Temprano M, Massari F, Sugai E, González A, Mauriño EC, Bogado C, Zanchetta JR, Bai JC. Impaired Bone Microarchitecture Improves After One Year On Gluten-Free Diet: A Prospective Longitudinal HRpQCT Study in Women With Celiac Disease. J Bone Miner Res 2017; 32(1):135-142.
  7. Mana DL, Zanchetta MB, Zanchetta JR. Retreatment with teriparatide: our experience in three patients with severe secondary osteoporosis Osteoporos Int 2017; 28(4):1491-1494.
  8. Spivacow, Abdala, del Valle, et al. Family history and biochemical diagnosis in 1948 kidney stone formers. Rev Nefrol Dial Traspl. 2017; 37(4):198-206
  9. Sánchez A, Zanchetta MB, Danilowicz K. Two cases of pregnancy- and lactation- associated osteoporosis successfully treated with denosumab. Clin Cases Miner Bone Metab 2016; 13(3):244-246.
  10. Sánchez A, Brun LR, Salerni H, Costanzo PR, González D, Bagur A, Oliveri B, Zanchetta MB, Farías V, Maffei LE, Premrou V, Mansur JL, Larroude MS, Sarli MA, Rey P, Ulla MR, Pavlove MM, Karlsbrum S, Brance ML. Effect of Denosumab on Bone Mineral Density and Markers of Bone Turnover Among Postmenopausal Women With Osteoporosis. J Osteoporos 2016:8738959.
  11. Zanchetta MB, Longobardi V, Bai JC. Bone and Celiac Disease. Curr Osteoporos Rep 2016;14(2):43-8.
  12. Zanchetta MB, Scioscia MF, Zanchetta JR. Bone microarchitecture in Rett syndrome and treatment with teriparatide: a case report. Osteoporos Int. 2016; 27(9):2873-2877.
  13. Boutroy S, Khosla S, Sornay-Rendu E, Zanchetta MB, McMahon DJ, Zhang CA, Chapurlat RD, Zanchetta J, Stein M, Bogado C, Majumdar S, Burghardt AJ, Shane E. Microarchitecture and Peripheral BMD Are Impaired in Postmenopausal Caucasian Women with Fracture Independently of Total Hip T-Score – an International Multicenter Study. J Bone Miner Res 2016; 31(6):1158-66.
  14. Zanchetta MB, Costa F, Longobardi V, Longarini G, Mazure RM, Moreno ML, Vázquez H, Silveira F, Niveloni S, Smecuol E, Temprano M de L, Hwang HJ, González A, Mauriño EC, Bogado C, Zanchetta JR, Bai JC. Significant bone microarchitecture impairment in premenopausal women with active celiac disease. Bone 2015; 76:149-157.
  15. Zanchetta MB, Diehl M, Buttazzoni M, Galich A, Silveira F, Bogado CE, Zanchetta JR. Assessment of bone microarchitecture in postmenopausal women on long term bisphosphonate therapy with atypical fractures of the femur. J Bone Miner Res 2014; 29(4):999-1004.
  16. Farias V, Zanchetta MB. Enfermedad de Paget poliostótica resistente a bifosfonatos tratada con denosumab. Reporte de caso. Actual Osteol 2014; 10(3).
  17. Spivacow FR, Sapag Durán A, Zanchetta MB. Hiperparatiroidismo normocalcémico. Medicina (B Aires) 2014; 74(6):457-461.
  18. Burghardt AJ, Pialat JB, Kazakia GJ, Boutroy S, Engelke K, Patsch JM, Valentinitsch A, Liu D, Szabo E, Bogado CE, Zanchetta MB, McKay HA, Shane E, Boyd SK, Bouxsein ML, Chapurlat R, Khosla S, Majumdar S. Multi-center precision of cortical and trabecular bone quality measures assessed by HR-PQCT. J Bone Miner Res 2013; 28(3):524-36.
  19. Sarli MA, Zanchetta MB, Rey PG, Spivacow FR. Tratamiento de la osteoporosis grave con teriparatide. Medicina (Buenos Aires) 2013; 73(5):428-432.
  20. Balogna MC, Zanchetta MB. Grave deterioro de la microarquitectura ósea inducido por desuso y denervación crónica. Actual Osteol 2013M 9(2):205-206.
  21. Zanchetta MB. Grave Alteración de la Microarquitectura Ósea en Síndrome de Sudeck. Actual Osteol 2013; 9(3):290-291.
  22. Zanchetta MB, Longobardi V. Significativa alteración de la microarquitectura ósea trabecular en una mujer joven con reciente diagnóstico de enfermedad celíaca.. Actual Osteol 2013; 9(1):79-81.
  23. Burghardt AJ, Pialat JB, Kazakia GJ, Boutroy S, Engelke K, Patsch JM, Valentinitsch A, Liu D, Szabo E, Bogado CE, Zanchetta MB, McKay HA, Shane E, Boyd SK, Bouxsein ML, Chapurlat R, Khosla S, Majumdar S. Multi-center precision of cortical and trabecular bone quality measures assessed by HR-PQCT. J Bone Miner Res 2013; 28(3):524-36.

Laboratorio de Biología Ósea (FCM-UNR)

  1. Brance ML, Pons-Estel BA, Quagliato NJ, Jorfen M, Berbotto G, Cortese N, Raggio JC, Palatnik M, Chavero I, Soldano J, Dieguez C, Sánchez A, Del Rio L, Di Gregorio S, Brun LR. Trabecular and cortical bone involvement in rheumatoid arthritis by DXA and DXA-based 3D modelling. Osteporosis Int, en prensa 2020.
  2. Zanchetta MB, Abdala R, Massari F, Rey Paula, Spivacow R, Miechi L, Longobardi V, Brun LR. Postmenopausal women with sarcopenia have higher prevalence of falls and vertebral fractures. Medicina (BsAs), en prensa 2020.
  3. Brance ML, Brun LR, Cóccaro NM, Aravena A, Duan S, Mumm S, Whyte MP. High Bone Mass From Mutation Of Low-Density Lipoprotein Receptor-Related Protein 6 (LRP6). Bone. En prensa 2020.
  4. Brance ML, Di Gregorio S, Pons-Estel BA, Quagliato NJ, Jorfen M, Berbotto G, Cortese N, Raggio JC, Palatnik M, Chavero I, Soldano J, Wong R, Del Rio L, Sánchez A, Brun LR. Prevalence of sarcopenia and whole-body composition in rheumatoid arthritis. J Clin Rheumatol. En prensa 2020.
  5. Haro JA, Brambilla L, Brun LR, Ibarra DA, Zuccari JI, Marchetto JM. Histology of ‘uncommon’ osteoderms of Glyptodon reticulatus Owen, 1845 (Mammalia, Xenarthra) from the late Pleistocene of Argentina and its systematic and developmental implications. J South Am Earth Sci En prensa 2020.
  6. Lupion P, Brun LR, Di Loreto VE. Efecto del acido zoledrónico en el hueso de ratas en crecimiento. Actual Osteol 2018 14(3): 168-177.
  7. Brance ML, Miljevic J, Tizziani R,  Taberna ME, Grossi GP, Toni P, Valentini E, Trepat A, Zaccardi J, Moro J, Finuci Curi B, Tamagnone N, Ramirez M, Severini J, Chiarotti P, Consiglio F, Piñesky R, Ghelfi A, Kilstein J, Street E, Moretti D, Oliveto V, Mariño M, Manera J, Brun LR. Serum 25-hydroxyvitamin D Levels in Hospitalized Adults with Community-Acquired Pneumonia. Clin Respir J. 2018.
  8. Brun LR, Lombarte M, Roma S, Perez F, Millán JL, Rigalli A. Increased calcium uptake and improved trabecular bone properties in intestinal alkaline phosphatase knockout mice. J Bone Miner Metab. 2018 36(6):661-667.
  9. Ramirez Stieben LA, Brance ML, Dobry R, Anca L, González A, López MI, Bayo S, Pustilnik E, Sánchez A, Brun LR. Niveles de 25(OH)-vitamina D en pacientes con diabetes mellitus tipo 2 con y sin síndrome metabólico. Actual Osteol 2017; 13(3):214-222.
  10. Sánchez A, Brun LR, Salerni H, Costanzo PR, Maffei L, Premrou V, Sarli MA, Rey P, Larroudé MS, Brance ML, Galich AM, González D, Bagur A, Oliveri B, Vega E, Zanchetta MB, Farías V, Mansur JL, Moggia MS, Ulla MR, Pavlove MM, Karlsbrum S. Evaluación de la respuesta densitométrica en pacientes con osteoporosis postmenopáusica tratadas con ranelato de estroncio o denosumab. Actual Osteol 2017; 13(1):9:16.
  11. Davis HM, Pacheco-Costa R, Atkinson EG, Brun LR, Gortazar AR, Harris J, Hiasa M, Bolarinwa SA, Yoneda T, Ivan M, Bruzzaniti A, Bellido T, Plotkin LI. Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging. Aging Cell. 2017; 16(3):551-563.
  12. Brun LR, Lombarte M, Maher MC, Retamozo C, Di Loreto V, Rigalli A. Efecto de la yerba mate (Ilex paraguariensis) sobre el hueso de ratas ovariectomizada. Actual Osteol 2016 12(3):188:196.
  13. Sánchez A, Brun LR, Salerni H, Costanzo PR, González D, Bagur A, Oliveri B, Zanchetta MB, Farías V, Maffei L, Premrou V, Mansur JL, Larroudé MS, Sarli MA, Rey P, Ulla MR, Pavlove MM, Karlsbrum S, Brance ML. Effect of denosumab on bone mineral density and markers of bone turnover among postmenopausal women with osteoporosis. J Osteoporos. 2016; 2016:8738959.
  14. Fina BL, Brun LR, Rigalli A. Increase of calcium and reduction of lactose concentration in milk by treatment with kefir grains and eggshell. Int J Food Sci Nutr. 2016; 67(2):133-40.
  15. Brun LR, Brance ML, Lombarte M, Maher C, Di Loreto VE, Rigalli A. Effects of yerba mate (Ilex paraguariensis) on histomorphometry, biomechanics, and densitometry on bones in the rat. Calcif Tissue Int. 2015; 97(5):527-34.
  16. Brance ML, Brun LR, Lioi S, Sánchez A, Abdala M, Oliveri B. Vitamin D levels and bone mass in rheumatoid arthritis. Rheumatol Int. 2015;35(3):499-505.
  17. Lupo M, Brance ML, Fina BL, Brun LR, Rigalli A. Methodology developed for the simultaneous measurement of bone formation and bone resorption in rats based on the pharmacokinetics of fluoride. J Bone Miner Metab. 2015; 33(1):16-22.
  18. Lombarte M, Brun LR, Brance ML, Bues F, Di Loreto VE. Efecto diferencial del ácido zoledrónico sobre el hueso trabecular y cortical de ratas ovariectomizadas. Actual Osteol 2014; 10(3):238-46.
  19. Brun LR, Galich AM, Vega E, Salerni  H, Maffei  L, Premrou  V, Costanzo PR, Sarli MA, Rey  P, Larroudé MS, Moggia MS, Brance ML, Sánchez  Strontium ranelate effect on bone mineral density is modified by previous bisphosphonate treatment. SpringerPlus.2014, 3:676.
  20. Brun LR, Brance ML, Lombarte M, Lupo M, Di Loreto VE, Rigalli A. Regulation of intestinal calcium absorption by luminal calcium content. Role of intestinal alkaline phosphatase. Mol Nutr Food Res 2014; 58(7):1546-51.
  21. Brance ML, Brun LR, Verónica VE, Lupo M, Rigalli A. Sequential treatment with monofluorophosphate and zoledronic acid in osteoporotic rats. Climacteric. 2014; 17(4):478-85.
  22. Brun LR, Lupo M, Delorenzi DA, Di Loreto VE, Rigalli A. Chicken eggshell as suitable calcium source at home. Int J Food Sci Nutr, 2013;64(6):740-3.
  23. Bivi N, Pacheco-Costa R, Brun LR, Murphy T, Farlow N, Robling AG, Bellido T, Plotkin LI. Absence of Cx43 selectively from osteocytes enhances responsiveness to mechanical force in mice. J Orthop Res. 2013;31(7):1075-81.
  24. Fina BL, Brance ML, Brun LR, Rigalli A. Fluoride inhibits in vitro and in vivo oxygen consumption and induces oxidative stress. Fluoride, 45(4): 325-30. 2012.
  25. Brun LR, Brance ML, Lupo M, Rigalli A. Relevamiento del contenido de calcio en lácteos de uso masivo. Actual Osteol 2012 8(3): 158-63.
  26. Bivi N, Condon K, Allen MR, Farlow N, Passeri G, Brun LR, Rhee Y, Bellido T, Plotkin LI. Cell autonomous requirement of connexin 43 for osteocyte survival: consequences for endocortical resorption and periosteal bone formation. J Bone Miner Res 2012; 27(2):374-389.
  27. Brun LR, Brance ML, Rigalli A. Luminal calcium concentration controls intestinal calcium absorption by modification of intestinal alkaline phosphatase activity. Br J Nutr 2012; 108:229-233.
  28. Brun LR, Roma SM, Pérez F, Rigalli A. Presencia de inflamación en el tejido óseo de ratas inducida por fluoruro de sodio. Actual Osteol 2012; 8(1): 19-28.
  29. Brun LR, Pera L, Rigalli A. Bone morphometry and differences in bone fluorine containing compounds in rats treated with NaF and MFP. Biomed Pharmacother. 64:1-6. 2010.

Laboratorio de Biología Osteoarticular, Ingeniería Tisular y Terapias Emergentes (LABOATEM)

  1. Miliane Gonçalves Gonzaga, Bruna Gabriela dos Santos Kotake, Fellipe Augusto Tocchini de Figueiredo, Sara Feldman, Edilson Ervolino, Maria Cecília Gorita dos Santos,| João Paulo Mardegan Issa. Effectiveness of rhBMP-2 association to autogenous, allogeneic, and heterologous bone grafts. Microsc Res Tech. 2019;1–7.
  2. Azevedo A, Prado AF, Feldman S,  de Figueiredo FA ,  dos Santos MCG,  M. Issa JP.  MMPs are Involved in Osteoporosis and are Correlated with Cardiovascular Diseases. Current Pharmaceutical Design. Curr Pharm Des 2018; 24(16):1801-1810.
  3. Coletta DJ, Missana LR, Martins T, Jammal MV, García LA, Farez N, De Glee T, Issa JPM, Feldman S. Synthetic Three-Dimensional Scaffold for Application in the Regeneration of Bone Tissue. Journal of Biomaterials and Nanobiotechnology 2018; 9:277-289.
  4. Cícero AM, Issa JPM, Feldman S. Matrices de tercera generación en la ingeniería de tejidos óseos. Matrices: ingeniería tisular ósea Actual Osteol 2017; 13(2): 157.
  5. Coletta D, Ibañez-Fonseca A, Missana L; Jammal M, Vitelli E, Aimone, Mariangels, Zabalza F, Mardegan Issa JP,Rodriguez-Cabello JC, Feldman S. Special focus: strategic directions in osteoinductionand biomimetics: Bone regeneration mediated by a bioactive and biodegradable ECM.like hidrogel base don elastin-like recobinamers. Tissue Engineering. 2017, 23:161-171.
  6. Alexandra Rodrigues Pereira da Silva, Tais Lício Macedo, Dante Jesús Coletta, Sara Feldman, Marivalda de Magalhães Pereira. Synthesis, characterization and cytotoxicity of Chitosan/Polyvinyl Alcohol/Bioactive Glass hybrid scaffolds obtained by lyophilization. Revista Materia 2016; V21(4):.964-973.
  7. Trivillin VS, Bruno LK, Gati DA, Stur M; Garabalino MA, Monti-Hughes A, Castillo J, Pozzi ECC, Wentzes L, Scolari H, Schwint AE, Feldman S. Boron neutron capture synovectoy (BNCS) as a potential therapy for theumatoid arthritis: radiobliological studies at RA-1 Nuclear Reactor in a model of antigen-induced artrhtis in rabbits. Radiat Environ Biophys 2016; 55:467-475 .
  8. Mortarino PA, Goy DP, Abramson DB, Cabello J, Bumaguin GE, Vitelli EJ, Toledo J, Saiiò L, Pezzotto SM, Mardegan Issa JP, Cointry GR, Feldman S. Emergin therapy in artrhritiis: Modulation of markers of the inflammatory process. Microc. Res. Tech. 2016; 79(2)89-97.
  9. Reina P, Cointry GR, Nocciolino L, Feldman S, Ferretti JL, Rittweger J, Capozza RF. Analysis of the independent power of age-related, anthropometric and mechanical factors as determinants of the structure of radius and tibia in normal adults. A pQCT study. J Musculoskelet Neuronal Interact 2015; 15(1):10-22.
  10. Trivillin VA, Abramson DV, Bumaguin GE, Bruno LJ, Garabalino MA, Monti Hughes A, Heber EM, Feldman S, Schwint AE. Boron Neutron Capture Synovectomy (BNCS) as a potential therapy for rheumatoid arthritis: boron biodistribution study in a model of antigen-induced arthritis in rabbits. Radiat Environ Biophys.
  11. Abramson DB, Cabello J, Bumaguin GE, Jamín A, Vitelli EJ, Zingoni N, Sarrió L, Feldman S, Cointry GR. Tolerancia oral en artritis experimental inducida por antìgeno en conejos por administración de hidrolizado de cartílago articular. Revista Inmunologia, editorial Elsevier,  Asociaciòn española de Inmunologia, 2014; 33(3):121-7
  12. Facciuto, F; Gargano SG, Cabral ME, Feldman S. Anàlisis antropométrico de la evolución del Genu Varo y Valgo Fisiològico en la Niñez a Través de la Medición de la Distancia Intercondílea Femoral Medial y la Distancia Intermaleolar Medial. Rev. Argentina de Anatomía Online 2014; 5:29-34.
  13. Coletta DJ, Lozano D, Rocha-Oliveira AA, Mortarino P, Bumaguin, GE, Vitelli, E, Vena R, Missana L, Jammal MV, Portal-Núñez S, Pereira M, Esbrit P, Feldman S. Characterization of hybrid bioactive glass-polyvinyl alcohol scaffolds containing a PTHrP-derived pentapeptide as implants for tissue engineering applications The Open Biomedical Engineering Journal 2014; (8):20-27.
  14. Capozza RF, Rittweger J, Reina P, Mortarino P, Nocciolino LM, Feldman S, Ferretti JL, Cointry GR. pQCT-assessed relationships between diaphyseal design and cortical bone mass and density in the tibiae of healthy sedentary and trained men and women. J Musculoskelet Neuronal Interact 2013; 13(2):195-205.
  15. Goy DP, Gorosito E, Costab HS, Mortarino P, Acosta Pedemonte N, Toledo J, Mansurb HS, Pereirab MM, Battaglino R, Seldman S. Hybrid Matrix Grafts to Favor Tissue Regeneration in Rabbit Femur Bone Lesions. The Open Biomedical Engineering Journal 2012; 6:85-91.
  16. Feldman S, Capozza RF, Mortarino PA, Reina PS, Ferretti JL, Rittweger J, Cointry GR. Site-and sex-specific effects on tibia structure in long-distance runners and untrained controls. Medicine and Science in Sports and Exercise (USA) 2012;44:1560-88.
  17. Yelin I, Mortarino P, Capozza RF, Cointry GR, Feldman S, Reina PS, Nocciolino LM, Ferretti JL. Importancia del entorno mecánico en la determinación biológica de la estructura ósea. Actualización del tema y análisis piloto de datos de individuos sedentarios y corredores.  Actual Osteol 2012; 8:86-108.
  18. Calgaro G, Cabral ME, Boglioli A, Bertoluzzo SM, Traina E, Feldman S. Anatomical Bases of the First Progress in Physiological Analysis of the Variation of the Childhood Intermalleolar Distance. Revista Argentina de Anatomía Online 2010; 1(4):117-149.
  19. Capozza, RF, Feldman S, Mortarino P, Reina PS, Shiest H, Ritweger J, Ferretti JL and Cointry G. Structural análisis of the human tibia by tomographic (pQCT) serial scans. Anatomy 2010; 216:470-481.

Laboratorio de Investigaciones Endocrinológicas Básicas y Clínicas (LIEByC)

  1. Cepeda SB, Sandoval MJ, Crescitelli MC, Rauschemberger MB, Massheimer The isoflavone genistein enhances osteoblastogenesis: signaling pathways involved. Journal of Physiology and Biochemistry 2020; 76.
  2. Agotegaray M, Blanco MG, Campelo AE, García E, Zysler R, Massheimer VL, De Rosa MJ, Lassalle V. β-cyclodextrin coating: improving biocompatibility of magnetic nanocomposites for biomedical applications. Journal of Materials Science: Materials in Medicine 2020; 31.
  3. Crescitelli MC, Rauschemberger MB, Cepeda SB, Sandoval MJ, Massheimer Role of estrone on the regulation of osteoblastogenesis. Molecular and Cellular Endocrinology 2019; Vol 498.
  4. Cutini PH, Massheimer VL. In vitroeffects of progesterone and the synthetic progestin medroxyprogesterone acetate on vascular remodeling. Molecular and Cellular Endocrinolology 498:110543, 2019. 
  5. Flamini DO, Valle MI, Sandoval MJ, Massheimer VL, Saidman SB. Electrodeposition study of polypyrrole-heparin and polypyrrole-salicylate coatings on Nitinol. Materials Chemistry and Physics 2018: 209:76-85.
  6. Andres NC, D’Elia NL, Ruso JM, Campelo AE, Massheimer VL, Messina P. Manipulation of Mg(2+)-Ca(2+) Switch on the Development of Bone Mimetic Hydroxyapatite. ACS Appl Mater Interfaces 2017: 9(18):15698-15710.
  7. Cepeda SB, Sandoval MJ, Rauschemberger MB, Massheimer VL. Beneficial role of the phytoestrogen genistein on vascular calcification. J Nutr Biochem 2017; 50:26-37.
  8. Montt-Guevara MM, Palla G, Spina S, Bernacchi G,  Cecchi E, Campelo AE, Shortrede JE Canu A, Simoncini T. Regulatory effects of estetrol on the endothelial plasminogen pathway and endothelial cell migration. Maturitas 2017; 99:1-9.
  9. Agotegaray MA, Campelo AE, Zysler RD, Gumilar F, Bras C, Gandini A, Lassalle VL. Magnetic nanoparticles for drug targeting: from design to insights into systemic toxicity. Preclinical evaluation of hematological, vascular and neurobehavioral toxicology. Biomater Sci 2017; 5(4), 772-783.
  10. Cutini PH, Rauschemberger MB, Sandoval MJ, Massheimer VL. Vascular action of bisphosphonates: In vitro effect of alendronate on the regulation of cellular events involved in vessel pathogenesis. J Mol Cell Cardiol 2016; 100:83-92.
  11. Agotegaray M, Campelo A, Zysler R, Gumilar F, Bras C, Minetti A, Lassalle V. Influence of chitosan coating on magnetic nanoparticles in endothelial cells and acute tissue biodistribution. J Biomater Sci Polym Ed 2016; 27(11):1069-1085.
  12. Cutini PH, Campelo AE, Massheimer VL. Differential regulation of endothelium behavior by progesterone and medroxyprogesterone acetate. J Endocrinol 2014; 220(3):179-193.
  13. Rauschemberger MB, Cutini PH, Sandoval MJ, Massheimer V. Efectos vasculares de raloxifeno y alendronato. Actualizaciones en Osteología, 9: 245-267, 2013.
  14. Campelo A, Cutini P, Massheimer V. Testosterone modulates platelet aggregation and endothelial cell growth through nitric oxide pathway. J Endocrinology, 213: 77-87, 2012.
  15. Campelo A, Cutini P, Massheimer V. Cellular actions of testosterone in vascular cells: mechanism independent of aromatization to estradiol, Steroids 77(11): 1033-1040, 2012.
  16. Cutini P, Campelo A, Agriello E, Sandoval M, Rauschemberger MB, Massheimer V. The role of sex steroids on cellular events involved in vascular disease. The Journal of Steroid Biochemistry and Molecular Biology 132: 322-330, 2012.
  17. Rauschemberger MB, Polini NN, Sola MO, Bonacorsi M, Massheimer VL. Receptor de estrógenos: variantes genéticas del esr1 y parámetros bioquímicos de riesgo cardiovascular. Revista Argentina de Endocrinología y Metabolismo, 49 (2): 53-61, 2012.
  18. Rauschemberger MB, Sandoval M, Massheimer V.  Cellular and Molecular actions displayed by Estrone on Vascular Endothelium. Mol Cell Endocrinol 339: 136-143, 2011.
  19. Cutini P, Massheimer V.   Role of Progesterone on the regulation of vascular muscle cells proliferation, migration and apoptosis.  Steroids, 75: 355-361, 2010.
  20. Sandoval M, Cutini P, Rauschemberger MB, Massheimer V. The soybean isoflavone Genistein modulates endothelial cell behaviour. British Journal of Nutriton, 104: 171-179, 2010.

Laboratorio de Investigaciones en Osteopatías y Metabolismo Mineral (LIOMM) (CICPBA-UNLP)

  1. Molinuevo MS, Schurman L, McCarthy AD, Cortizo AM, Tolosa MJ, Gangoiti MV, Arnol V, Sedlinsky C. Effect of Metformin on bone marrow progenitor cell differentiation: In Vivo and In Vitro Studies. J Bone Miner Res 2010; 25:211-21.
  2. McCarthy AD, Curciarello R, Castiglione N, FernandezTayeldin M, Costa D, Arnol V, Prospitti A, Aliano A, Archuby D, Graieb A, Torres MJ, Etcheverry SB, Apezteguia MC. Universal versus selective screening for the detection, control and prognosis of Gestational Diabetes mellitus in Argentina. Acta Diabetologica 2010; 47:97-103.
  3. Fernandez JM, Molinuevo MS, Cortizo AM, McCarthy AD, Cortizo MS. Characterization of poly-e-caprolactone/polyfumarate blends as scaffolds for bone tissue engineering. J Biomater Sci Polymer 2010; 21:1297-1312.
  4. Fernandez JM, Molinuevo MS, Cortizo MS, Cortizo AM. Development of an osteoconductive PCL-PDIPFhydroxyapatite composite scaffold for bone tissue engineering. J Tissue Eng Regen Med. 2011; 5:e126-35.
  5. Fernandez JM, Cortizo MS, Cortizo AM, Abraham GA. Osteoblast Behavior on Novel Porous Polymeric Scaffolds. J Biomater Tissue Eng 2011;86-92.
  6. Sedlinsky C, Molinuevo MS, Cortizo AM, Tolosa MJ, Felice J, Sbaraglini ML, Schurman L, McCarthy AD. Metformin prevents anti-osteogenic in vivo and ex vivo effects of Rosiglitazone in rats.. Eur J Pharmacol 2011; 668(3):477-85.
  7. Felice JL, Cortizo AM, Sedlinsky C, Schurman L, McCarthy AD. Efectos in vivo de Metformina sobre las alteraciones de la micro-arquitectura ósea asociadas al Síndrome Metabólico inducido por Fructosa en ratas. Revista Argentina de Endocrinologia y Metabolismo (RAEM) 2011; 48(4):193-9.
  8. Cortizo MC, Oberti TG, Cortizo MS, Cortizo AM, Fernandez Lorenzo de Mele M. Chlorexidinedelibery system from titanium/polybenzylacrylate coating: Evaluation of cytotoxicity and bacerail adhesion. J Dentistry 2012; 40: 329-337.
  9. Cortizo AM, Ruderman G, Correa G, Mogilner IG, Tolosa EJ. Effect of surface topography of collagen scaffolds on cytotoxicity and osteoblast differentiation. J Biomater Tissue Eng 2012; 2(2): 125-132.
  10. Gangoiti MV, McCarthy AD, Cortizo AM. Efectos de los productos de glicación avanzada (ages) y alendronato sobre el desarrollo osteoclástico: posibles mecanismos de acción. Revista Argentina de Endocrinologia y Metabolismo (RAEM) 2012; 49(1):12-19.
  11. Tolosa MJ, Chuguransky SR, Schurman L, Sedlinsky C, Cortizo AM1, McCarthy AD, Molinuevo MS. La diabetes altera el potencial osteogénico de células progenitoras de médula ósea. Efectos del tratamiento con metformina. Rev Argent Endocrinol Metab (RAEM) 2012; 49:70-76.
  12. Gangoiti MV, Anbinder PS, Cortizo AM, McCarthy AD. Morphological changes induced by advanced glycation endproducts in osteoblastic cells: Effects of co-incubation with alendronate. Acta Histochem 2013; 115(7):649-57.
  13. Fernández JM, Molinuevo MS, Sedlinsky C, Schurman L, Cortizo AM, McCarthy AD. Strontium ranelate prevents the deleterious action of advanced glycation endproducts on osteoblastic cells via calcium channel activation. Eur J Pharmacol 2013; 13:41-47.
  14. Tolosa MJ, Chuguransky SR, Sedlinsky C, Schurman L, McCarthy AD, Molinuevo MS, Cortizo AM. Insulin-deficient Diabetes-induced bone microarchitecture alterations are associated with a decrease in the osteogenic potential of bone marrow progenitor cells. Preventive effects of metformin. Diabetes Res Clin Pract 2013; 101(2):177-86.
  15. Gangoiti MV, Arnol V, Cortizo AM, McCarthy AD. Advanced Glycation Endproducts and Alendronate differentially inhibit early and late osteoclastogenesis in vitro. J Diabetes & Metab 2013; 4(6) 1-7.
  16. McCarthy AD, Molinuevo MS, Cortizo AM. AGEs and Bone Ageing in Diabetes Mellitus. J Diabetes & Metab 2013; 4(6):1-8.
  17. Felice JI, Gangoiti MV, Molinuevo MS, McCarthy AD, Cortizo AM. Effects of a Metabolic Syndrome induced by a Fructose-Rich Diet on Bone Metabolism in Rats. Metabolism Clinical and Exp 2014; 63(2) 296-305.
  18. Fernandez JM, Cortizo MS, Cortizo AM. Fumarate/Ceramic composite based scaffolds for tissue Engineering: evaluation of hydrophylicity, degradability, toxicity and biocompatibility. J Biomater Tissue Eng 2014; 4:227-234.
  19. Fernandez JM, Molinuevo MS, McCarthy AD, Cortizo AM. Strontium Ranelate stimulates the activity of bone-specific alkaline phosphatase: interaction with Zn2+ and Mg2+. BioMetals 2014; 27(3):601-7.
  20. Braziunas MD and Cortizo AM. Vitamin D-VDR signaling in bone cells. Physiol Mini Review 2014; 7(6):77-92.
  21. Sbaraglini ML, Molinuevo MS, Sedlinsky C, Schurman L, McCarthy AD. Saxagliptin affects long-bone microarchitecture and decreases the osteogenic potential of bone marrow stromal cells. Eur J Pharmacol 2014; 727:8-14.
  22. Lastra ML, Molinuevo MS, Giussi JM, Allegretti PE, Blaszczyk-Lezak I, Mijangos C, Cortizo MS. Tautomerizable β-ketonitrile copolymers for bone tissue engineering: Studies of biocompatibility and cytotoxicity. Mater Sci Eng C Mater Biol Appl. 2015; 51:256-62.
  23. Alfano AL, Fernandez JM. Induction of topographical changes in PCL scaffolds for bone tissue engineering: biocompatibility and cytotoxicity evaluations. Journal of Biomaterials and Tissue Engineering 2015;142-149.
  24. Belluzo MS, Medina LF, Cortizo AM, Cortizo MS. Ultrasonic compatibilization of polyelectrolyte complex based on polysaccharides for biomedical applications”. Ultrasonics Sonochemistry 2016; 30:1-8.
  25. McCarthy AD, Cortizo AM, Sedlinsky C. Metformin revisited: Does this regulator of AMP-activated protein kinase secondarily affect bone metabolism and prevent diabetic osteopathy. World J Diabetes 2016; 7(6):122-33.
  26. Cortizo AM, Ruderman G, Mazzini FN, Molinuevo MS, Mogilner IG. Novel vanadium-loaded ordered collagen scaffold promotes osteochondral differentiation of bone marrow progenitor cells” Int J Biomater 2016.
  27. Fernandez JM, Oberti TG, Vikingsson L, Gómez Ribelles JL, Cortizo AM. Biodegradable polyester networks including hydrophilic groups favor BMSCs differentiation and can be eroded by macrophage action. Polymer Degradation and Stability 2016; 130:38-46.
  28. Lino AB, Fernández JM, Molinuevo MS, Cortizo AM, McCarthy AD. Efectos in vivo del ranelato de estroncio sobre células progenitoras de médula ósea de ratas diabéticas. Actual Osteol 2016; 12(2):78-86.
  29. Chuguransky SR, Cortizo AM, McCarthy AD. Alendronate modulates the fate of bone marrow progenitor cells. Role of AGEs. BioMed Research International 2016.
  30. Lastra ML, Molinuevo, MS, Cortizo AM, Cortizo MS. Fumarate copolymer – chitosan crosslinked scaffold directed to osteochondrogenic tissue engineering. Macromolecular Bioscience 2017; 17(5).
  31. Felice JI, Schurman L, McCarthy AD, Sedlinsky C, Aguirre JI, Cortizo AM. Effects of fructose-induced metabolic syndrome on rat skeletal cells and tissue, and their responses to metformin treatment. Diabetes Res ClinPract 126, 202-213, 2017.
  32. Molinuevo MS, Fernández JM, Schurman L, Cortizo AM, McCarthy AD, Sedlinsky C. Advanced Glycation End Products and Strontium Ranelate Promote Osteogenic Differentiation of Vascular Smooth Muscle Cells In Vitro: Preventive Role of Vitamin D. Molecular and Cellular Endocrinology 2017; 450:94-104.
  33. Lino AB, McCarthy, AD, Fernandez JM. Evaluation of strontium-containing PCL-PDIPF scaffolds for bone tissue engineering: in vitro and in vivo studies. Annals of Biomedical Engineering 2019; 47(3):902-912.
  34. Besada LN, Peruzzo P, Cortizo AM, Cortizo Ms. Preparation, characterization and in vitro activities evaluation of triblock copolymers-based polymersomes for drugs delivery. Journal of Nanoparticle Research 2018; 20:67.
  35. Álvarez-Lloret P, Fernández JM, Molinuevo MS, Lino AB, Ferretti JL, Capozza RF, Cortizo AM, McCarthy AM. Multi-scale approach for the evaluation of bone mineralization in strontium ranelate treated diabetic rats. Biological Trace Element Research 2018.
  36. Fernandez JM, Gangoiti MV, Lino A, Cortizo MC, Cortizo AM, Molinuevo MS. Alendronate modulate the dental pulp progenitor cells plasticity. Oral Health and Medicine 2018;2.
  37. Lastra ML, Molinuevo MS, Blaszczyk-Lezak I, Mijangos C, Cortizo MS. Nanostructured fumarate copolymer-chitosan crosslinked scaffold: An in vitro osteochondrogenesis regeneration study. J Biomed Mater Res A 2018; 106(2):570-579.
  38. Bravi Constantino L, Oberti TG, Cortizo AM, Cortizo MS. Matrices based on lineal and star fumarate-metha/acrylate copolymers for bone tissue engineering: Characterization and biocompatibility studies. J Biomed Mater Res, Part A 2019; 107A:195-203.
  39. Torres ML, Fernandez JM, Dellatorre FG, Cortizo AM, Oberti TG. Purification of Alginate Improves its Biocompatibility and Eliminates Cytotoxicity in Matrix for Bone Tissue Engineering. Algal Research 2019; 40:101499.
  40. Zurriaga Carda J, Lastra ML, Antolinos CM, et al. A cell-free approach with a supporting biomaterial in the form of dispersed microspheres induces hyaline cartilage formation in a rabbit knee model”. J Biomed Mater Res B ApplBiomater 2019.
  41. Bravi Costantino ML, Cortizo MS, Cortizo AM, Oberti TG. Osteogenic scaffolds based on fumaric/N,N-diisopropylacrylamide copolymers: designed, properties and biocompatibility studies. Eur Polymer J. En prensa 2019.
  42. Gangoiti MV, Peruzzo PJ. Cellulose nanocrystal reinforced acylglycerol-based polyurethane foams.. eXPRESS Polymer Letters Vol.14 (2020). En prensa 2020.

Laboratorio de Metabolismo Fosfocálcico y Vitamina D “Dr. Cañas”

  1. Rodriguez, G. Díaz de Barboza, R. Ponce, V. Merico, S. Garagna, N. Tolosa de Talamoni. Spermatocyte apoptosis, which involves intrinsec and extrinsec apoptotic pathways, explains the sterility of Graomys centralis x Graomys griseoflavus male hybrids. Reproduction, Fertility and Development 2010; 22:477-488.
  2. Pérez A, Centeno V, Tolosa de Talamoni NJ. Molecular mechanisms involved in the enhancement of mitochondrial malate dehydrogenase activity by calcitriol in chick intestine. Nutr Biochem 2010; 1232-1237.
  3. Miras M, Ochetti M, Martín S, et al. Serum levels of adiponectin and leptin in children born small for gestational age: relation to insulin sensitivity parameters. Pediatric Endocrinol. & Metabolism 2010; 23:463-472.
  4. Vitamin D receptor genotypes are associated with the bone mass in patients with Turner syndrome. Peralta López, M. Miras, L. Silvano, A. Pérez, L. Muñoz, V. Centeno, G. Sobrero, M. Ulla, N. Tolosa de Talamoni. J Pediatric Endocrinol. & Metabolism 2011; 24:307-312.
  5. Silvano, M. Miras, A. Pérez, G. Picotto, G. Díaz de Barboza, L. Muñoz, S. Martin, G. Sobrero, P. Armelini, V, Tolosa de Talamoni, N. Comparative analysis of clinical, biochemical and genetic aspects associated with bone mineral density in small for gestational age children. J Pediatric Endocrinol & Metabolism 2011; 24:511-518.
  6. Centeno, G. Picotto, A. Pérez, A. Alisio, N. Tolosa de Talamoni. Intestinal Na+/Ca2+ exchanger gene and protein expression are regulated by 1,25(OH)2D3 in vitamin D- deficient chicks. Arch. Biochem. & Biophysics 2011; 509:191-196.
  7. Carpentieri, G. Díaz de Barboza, V. Areco, M. Peralta López, N. Tolosa de Talamoni. New perspectives in melatonin uses. Pharmacol. Research 2012; 65:437-444.
  8. Rivoira M, Marchionatti A, Centeno V, Peralta López M, Tolosa de Talamoni N. Sodium deoxycholate inhibits duodenal calcium absoprtion through oxidative stress and apoptosis. Comparative Biochemistry & Physiology [A] 2012; 162:397-405.
  9. Bohl L, Liaudat C, Picotto G, Marchionatti A, Narvaez C, Welsh J, Rodriguez V, Tolosa de Talamoni N. Buthionine sulfoximine and 1,25-dihydroxyvitamin d induce apoptosis in breast cancer cells via induction of reactive of reactive oxygen species. Cancer Investigation 2012; 30:560-570. 
  10. Peralta López M, Centeno V, Silvano L, Pérez A, Muñoz L, Sobrero G, Ulla M, Tolosa de Talamoni NJ. Association of vitamin D receptor gene Cdx2 polymorphism with bone markers in Turner syndrome patients. Pediatric Endocrinol. & Metabolism 2012; 25:669-671.
  11. Picotto, A. Liaudat, L. Bohl, N. Tolosa de Talamoni. Molecular aspects of vitamin D anticancer activity. Cancer Investigation 2012; 30:604-614.
  12. Marchionatti A, Pacciaroni A, Tolosa de Talamoni N. Effects of quercetin and menadione on intestinal calcium absorption and the underlying mechanisms. Comp Biochem. & Physiol. Part A 2013; 164:215-220.
  13. Rodríguez V, Rivoira M, Marchionatti A, Pérez A, Tolosa de Talamoni N. Ursodeoxycholic acid and deoxycholic acid: a good and a bad bile acid for the intestinal Ca2+ absorption. Arch. of Biochem.& Biophysics 2013; 540:19-25,.
  14. Carpentieri A, Marchionatti A, Areco V, Pérez A, Centeno V, Tolosa de Talamoni N. Antioxidant and antiapoptotic properties of melatonin restore intestinal calcium absorption altered by menadione. Molecular and Cellular Biochemistry 2014; 387:197-205.
  15. Liaudat A, Bohl L, Tolosa de Talamoni N, Maletto B, Pistoresi-Palencia M, Picotto G. Oxidative stress, cell cycle arrest and differentiation contribute to the antiproliferative action of BSO and calcitriol on Caco-2 cells. Anticancer Drugs 2014; 25:810-818.
  16. Díaz de Barboza G, Rodríguez V, Ponce R, Theiler G, Maldonado C, Tolosa de Talamoni N. Association of celular and molecular alterations in Leydig cells with germ cell apoptosis in testes of Graomys griseoflavus x Graomys centralis male hybrids. Acta Histochemica 2014; 116:604-14.
  17. Martin S, Muñoz L, Pérez A, et al. Clinical and molecular studies relative to bone metabolism in patients with congenital adrenal hiperplasia. J Pediatric Endocrinol. & Metabolism 2014; 27:1161-1166.
  18. Rivoira M, Rodríguez V, Peralta López M, Tolosa de Talamoni N. Time dependent changes in the intestinal Ca2+ absorption in rats with type I Diabetes mellitus are associated with alterations in the intestinal redox state. Biochimica et Biophysica Acta. Molecular Basis of Disease 2015; 1852:386-94.
  19. Díaz de Barboza G, Guizzardi S, Tolosa de Talamoni N. Molecular aspects of the intestinal calcium absorption. World Journal of Gastroenterology 2015; 21:7142-54.
  20. Areco V, Rivoira M, Rodriguez V, Marchionatti A, Carpentieri A, Tolosa de Talamoni N. Dietary and pharmacological compounds altering the intestinal Ca2+ absorption in humans and animals. Nutrition Research Reviews 2015; 28:83-99.
  21. VA Rodríguez, MA Rivoira, A del V. Pérez, AM Marchionatti, NG Tolosa de Talamoni. Ursodeoxycholic and deoxycholic acids: differential effects on intestinal Ca2+ uptake, apoptosis and autophagy of rat intestine. Archives of Biochemistry and Biophysics 2016; 591:28-34.
  22. V Areco, V Rodríguez, A Marchionatti, A Carpentieri, N Tolosa de Talamoni. Melatonin not only restores but also prevents the inhibition of the intestinal Ca2+ absorption caused by glutathione depleting drugs”, Comp. Biochem. and Physiol. [A] 2016; 197:16-22.
  23. AM Marchionatti, A del V Pérez, MA Rivoira, VA Rodríguez, NG Tolosa de Talamoni. Lithocholic acid: a new emergent protector of the intestinal calcium absorption under oxidant conditions. Biochemistry and Cell Biology 2017; 95:273-79.
  24. Díaz de Barboza G, Guizzardi S, Moine L, Tolosa de Talamoni N. Oxidative stress, antioxidants and intestinal calcium absorption. World Journal of Gastroenterology 2017; 23:2841-2853.
  25. L Moine, G Díaz de Barboza, M Benedetto, N Tolosa de Talamoni. Glutamine protects intestinal calcium absorption against oxidative stress and apoptosis. Comparative Biochem. & Physiol. [A] 2017; 212:64-71.
  26. L Bohl, S Guizzardi, V Rodriguez, L Hinrichsen, V Rozados, D Cremonezzi, N Tolosa de Talamoni, G Picotto. Combined calcitriol and menadione reduces experimental murine triple negative breast tumor. Biomedicine & Pharmacoterapy 2017; 94:21-26.
  27. Rodriguez V, Rivoira M, Guizzardi S, Tolosa de Talamoni N. Naringin prevents the inhibition of intestinal Ca2+ absorption induced by a fructose rich diet. Archives of Biochemistry and Biophysics 2017; 636:1-10.
  28. Rivoira M, Rodriguez V, Guizzardi S, Tolosa de Talamoni N. Naringin prevents bone loss in a rat model of type 1 Diabetes mellitus. Archives of Biochemistry and Biophysics 2018; 636:56-63.
  29. A Marchionatti, M Rivoira, V Rodríguez, A Pérez, N Tolosa de Talamoni. Molecular mechanisms triggered by bile acids on intestinal Ca2+ absorption. Current Medicinal Chemistry 2018; 25:2122-32.
  30. V Rodriguez, L Plavnik, N. Tolosa de Talamoni. Naringin attenuates liver damage in streptozotocin-induced diabetic rats. Biomedicine & Pharmacoterapy 2018; 105:95-102.
  31. L Moine, M Rivoira, G Díaz de Barboza, A Pérez, Tolosa de Talamoni N. Glutathione depleting drugs, antioxidants and intestinal calcium absorption. World Journal of Gastroenterology, 2018; 24:4979-4988.
  32. Bessone C, Fajreldines H, Díaz de Barboza G, Tolosa de Talamoni N, Allemandi D, Carpentieri A, Quinteros D. Protective role of melatonin on retinal ganglionar cell: In vitro an in vivo evidences. Life Sci 2019; 218:233-40.
  33. L Moine, A Pérez, C Maldonado, N Tolosa de Talamoni, G Díaz de Barboza. Glutamine protects both transcellular and paracellular pathways of chick intestinal calcium absorption under oxidant conditions. C Biochem. & Physiol. [A] 2019; 238:110553.
  34. Guizzardi S, Picotto G, Rodriguez V, Welsh J, Narvaez C, Bohl L, Tolosa de Talamoni N.  Combined treatment of menadione and calcitriol increases the antiproliferative effect by promoting oxidative/nitrosative stress, mitochondrial dysfunction and autophagy in breast cancer MCF-7 cells. Canadian Journal of Physiology and Pharmacology, 98: 548-556, 2020.
  35. Pérez A, Rivoira MA, Rodríguez V, Marchionatti A, Tolosa de Talamoni N. Role of mitochondria in the differential action of sodium deoxycholate and ursodeoxycholic acid on rat duodenum. Canadian Journal of Physiology and Pharmacology, 2020, en prensa.
  36. Kohan R, Collin A, Guizzardi S, Tolosa de Talamoni N, Picotto G. Reactive oxygen species in cancer: a paradox between pro and anti-tumor activity.  Cancer Chemotherapy and Pharmacology, 86: 1-13, 2020.
  37. Areco V, Kohan R, Talamoni G, Tolosa de Talamoni N, Peralta López ME. Intestinal calcium absorption revisited: a molecular and clinical approach. World Journal of Gastroenterology, 26: 3344- 3364, 2020.
  38. Rivoira MA, Rodriguez V, Talamoni G, Tolosa de Talamoni N. New perspectives in the pharmacological potential of naringin in medicine. Current Med Chem., en prensa 2020.

Laboratorio de Osteopatías Metabólicas y Laboratorio de Osteoporosis y Enfermedades Metabólicas Óseas

  1. Gonzales Chaves MMS, Marote C, Pellegrini GG, Pighin A, de Landeta MC, Lifshitz F, Friedman SM, Mandalunis P, Zeni SN. Bone mass recovery of osteopenic-vitamin D insufficient rats from strontiumranelate treatment: Does the response depend on vitamin D nutritional statusor on source of vitamin D (D2 vs. D3)?. J Musc Skelet Res 13 (3): 95-108, 2010.
  2. Macri EV, Gonzales Chaves MMS, Rodriguez PN, Mandalunis P, Zeni SN,  Lifshitz F. Friedman SM. High-fat diets affect energy and bone metabolism in growing rats. Eur J Nutr. 51(4):399-406, 2012.
  3. Pellegrini GG, Gonzales Chaves MMS, Fajardo M, Ponce GM, Toyos GI, Lifshitz F, Friedman S M, Zeni SN. Salivary bone turnover markers in healthy pre and postmenopausal women: daily and seasonal rhythm. Clin Oral Invest 16(2):651-7, 2012.
  4. Marotte C, Weisstaub A, Bryk G, Olguin MC, Posadas M, Lucero D, Schreier L, Pita Martín de Portela ML, Zeni SN. Effect of dietary calcium (Ca) on body composition and Ca metabolism during growth in genetically obese (β) male rats. Eur J Nutr. 52 (1):297-305, 2013.
  5. Marotte C, Gonzales Chaves MMS, Pellegrini GG, Friedman SM, Mandalunis P, Zeni SN. Low protein intake magnifies detrimental effects of ovariectomy and vitamin D on bone. Calcif Tissue Int. 2013 Aug; 93(2):184-92.
  6. Weisstaub AR, Abdala V, Gonzales Chaves MMS, Mandalunis P, Zuleta A, Zeni SN. Polidextrose enhances calcium absorption and bone mineralization in ovariectomized rats. Intern Food Sc 2013.
  7. Marotte C, Bryk G, Gonzales Chaves MMS, Lifshitz F, Pita Martín de Portela ML, Zeni SN. Low dietary calcium and obesity: A comparative study in genetically obese and normal rats during early growth. Eur J Nutr. 2014; 53(3):769-78.
  8. Bryk G, Zeni Coronel M, Pellegrini G, Mandalunis P, Rio ME, de Portela ML, Zeni SN. Effect of a combination GOS/FOS® prebiotic mixture and interaction with calcium intake on mineral absorption and bone parameters in growing rats. Eur J Nutr. 2015; 54(6):913-23.
  9. Antonenko O, Bryk G,Brito G, Pellegrini G, Zeni SN.Oral health in young women having a low calcium and vitamin D nutritional status. Clin Oral Investig 19(6):1199-206, 2015.
  10. Bryk G, Zeni Coronel M, Lugones C, Mandalunis P, Rio ME, Gualtieri AF, de Portela ML, Zeni SN. Effect of a mixture of GOS/FOS® on calcium absorption and retention during recovery from protein malnutrition: experimental model in growing rats. Springer-Verlag Berlin Heidelberg Eur J Nutr 2016; 55:2445-2458,.
  11. Antonenko O, Seijo M, Brito G, Gualtieri AF, Pellegrini G, Zeni SN. Low Calcium Intake and Hypovitaminosis D Negatively Affect Oral Health in Young Men. Austin J Dent 4 (7): 1-8, 2017.
  12. Seijo M, Bryk G, Zeni Coronel M, Bonnano M, Rio ME, PM de Portela ML, Zeni SN. Effect of Adding a Galacto-Oligosaccharides/Fructo-Oligosaccharides (GOS/FOS®) Mixture to a Normal and Low Calcium Diet, on Calcium Absorption and Bone Health in Ovariectomy-Induced Osteopenic Rat. Calcif Tissue Int.2019;104(3):301-312.
  13. Davison MR, Lyardet L, Preliasco M, Yaful G, Torres P, Pellegrini GG, Zeni SN. Aminobisphosphonate-treated ewes as a model of osteonecrosis of the jaw and of dental implant failure. J Periodontol 2019.
  14. Marotte C, Bonanno MS, Zeni Coronel M, Avendaño ME, Pita Martín de Portela ML, Zeni SN. Calcium Intake is Associated to Changes in the Interplay between Bone, Pancreas and Fat Tissue in the Control of Glucose Homeostasis- Experimental Study. Austin J Nutr Metabol 6 (1): 1-8 id 1063, 2019.
  15. Suarez C, Ferreira Monteiro A, Macri E, Chiarenza A, Zeni S, Rodríguez P, Boyer P, Friedman S. High-fat diets and body composition over two generations. An experimental study. Endocrinol Nutr 59(4):232-8, 2012.
  16. Pellegrino N, Giacomino MS, Dupraz E, Rodriguez V, Ferreyra V, Apro N, Zeni SN, Pita Martin de Portela ML. Formulación y diseño de alimentos para la tercera edad. Actualizacion en Nutricion 13(1): 21-28, 2012.
  17. Bryk G, Zeni Coronel Magalí, Medina D, Pellegrini G, Pita Martín de Portela ML, Zeni SN. Efecto de una mezcla de galactooligosacáridos (GOS)/ fructooligosacáridos (FOS) sobre la absorción intestinal y  retención ósea de calcio, fosforo y magnesio: modelo experimental en ratas durante el crecimiento normal. Actualizaciones en Osteologia 9: 243-253, 2013.
  18. Marotte C. Zeni SN.Especies reactivas de oxigeno y su efecto sobre la actividad de las células oseas. Argentina Acta Bioquím. Clín Latinoamer 47:661-674, 2013.
  19. Bryk G, Gonzales Chaves M, Lugones C, Pellegrini G, Mandalunis P, Pita Martín de Portela ML, Zeni SN. Utilidad de una mezcla prebiótica para aumentar la absorción y biodisponibilidad de Ca durante el crecimiento normal y durante la recuperación de una malnutrición proteica: modelo experimental en ratas. Actual Osteol 2015; 11(1):19-37.
  20. Oliveri B, Zeni SN. Hipovitaminosis D y desarrollo de Síndrome Metabólico. Acta Bioq Clin Latinoam 50(3):375-385, 2016.
  21. Zeni SN. Conexiones entre tejido óseo y tejido graso: efecto de la obesidad sobre la salud ósea. Acta Bioq Clin Latinoam 50(3):387-393, 2016.
  22. Dupraz H, Zeni SN, Rio ME. Transición nutricional y obesidad epidémica. Caracteristicas en la edad escolar. Rev Farm 158(2):3-19, 2016.
  23. Seijo M, Oliveri B, Deferrari JM, Casco C, Zeni SN. Marcadores de formación y resorción ósea y su utilidad para determinar el final del periodo de aposición ósea. Actual Osteol 13(1):28-36, 2017.
  24. Davison Mr, Lyardet L, Preliasco M, Yaful G, Torres P, Duran F, Pellegrini Gg, Zeni S N.  Desarrollo de un modelo experimental de osteonecrosis de mandibula asociada al tratamiento cronico con aminobisfosfonatos. Actual Osteol 13(2):104-115, 2017.
  25. Pellegrini GG, Gonzalez-Chaves MMS, Orzuza R, Zeni SN. Estudio preliminar sobre las propiedades de biocompatibilidad y osteoconductividad de un nuevo injerto de hueso bovino. Actual Osteol 13(2):116-124, 2017.
  26. Dupraz H, Zeni SN, Rio ME. Transición nutricional y obesidad epidémica. Características en la edad escolar. Rev. Farm.158:3-19, 2017.
  27. Bonnano M, Rey Saravia M, Seijo M, Zeni SN. Rol de las células óseas más allá del remodelamiento óseo. Actual Osteol 15(2):78:93, 2019.
  28. Mastaglia S, Watman N, Oliveri B: Intravenous pamidronate treatment and pregnancy: its effects on mother and infant bone health. Osteoporosis Int, 21:1959-1962, 2010.
  29. Mastaglia SM, Seijo M, Muzio D, Oliveri B. Hipovitaminosis D en mujeres mayores de 65 años efecto de la administración de tres dosis diferentes de vitamina D. Revista Argentina de Rehabilitación: 5: 30-35, 2010.
  30. Wittich A, Bagur A, Mautalen C, Cristofari A, Escobar O, Carrizo G, Oliveri B. Epidemiology of hip fractures in Tucuman Argentina, Osteoporosis Int 21:1803-1807, 2010.
  31. Mastaglia SR. Seijo M, Muzio D, Somoza J, Núñez M, Oliveri B. Effect of Vitamin D Nutritional Status on Muscle Function and Strength in Healthy Women Aged over Sixty-Five Years. J Nutr  Health Aging 15:349-354, 2011.
  32. Matthew Austin, Yu-Ching Yang, Eric Vittinghoff, et al. Relationship between Bone Mineral Density Changes with Denosumab treatment and risk reduction for vertebral and Nonvertebral Fractures. J Bone Mineral Res 27: 687-693, 2012.
  33. M Seijo, S Mastaglia, G Brito, J Somoza, B Oliveri. ¿Es equivalente la suplementacion diaria con vitamina D2 o vitamina D3 en adultos mayores? Medicina (Buenos Aires), 72:195-200, 2012.
  34. Mastaglia S, Solís F, Bagur A, Mautalen C, Oliveri B. Increase in android fat mass with age in healthy women with normal body mass index. J Clin Densitom 15: 159-64, 2012.
  35. GM Brito, SR Mastaglia, C Goedelman, M Seijo, J Somoza, B Oliveri. Estudio exploratorio de la ingesta y prevalencia de Vitamina D en mujeres ≥de 65 años que viven en su hogar familiar o en residencias para autoválidos de la Ciudad de Buenos Aires, Argentina. Nutr Hospital 28:797-803, 2013.
  36. Mastaglia S, Somoza J, González D, Oliveri B. Osteomalacia Tumoral. Actual Osteol 9:194-202, 2013.
  37. Sánchez A, Oliveri B, Mansur JL, Fradinger E. Guía Práctica de la Federación Argentina de Sociedades de Endocrinología. Diagnóstico, Prevención y Tratamiento de la Hipovitaminosis D. Rev Arg Endocrinol Metab 50: 140-156, 2013.
  38. Mastaglia SR, Watson DZ, Oliveri B. Controversia sobre los niveles de vitamina D para la salud ósea propuestos por el Instituto de Medicina de Estados Unidos y la Comunidad Médica Internacional. Actual Osteol 9:207-216, 2013.
  39. G Drelichman, N Fernández Escobar, N Basack, et al. Enfermedad de Gaucher: un informe del Registro Internacional de Gaucher y Grupo Argentino de Diagnóstico y Tratamiento de la Enfermedad de Gaucher. Hematología 17:4-16, 2013.
  40. G Drelichman, N Fernández Escobar, N Basack, et al. Consenso para la Enfermedad de Gaucher: Grupo Argentino de Diagnóstico y Tratamiento de la Enfermedad de Gaucher. Hematología 17:25-60, 2013.
  41. Brance ML, Brun LR, Lioi S, Sanchez A, Abdala M, Oliveri B. Vitamin D levels and bone mass in rheumatoid arthritis. Rheumatol Int: 35:499-505, 2015.
  42. Jercovich F, Moncet D, Babini S, Zoppi JA, Graciolli F, Oliveri B. Osteomalacia Oncogénica. Presentación de dos casos. Medicina (Buenos Aires) 75:37-40, 2015.
  43. Bagur A, Mastaglia S, Oliveri B, Gonzalez D, Sarnacki E, Fernandez C, Mautalen C: Baja masa idiopática y osteoporosis secundaria en mujeres premenopausicas. Actual Osteol 11:12-18, 2015.
  44. B Oliveri, SR Mastaglia, GM Brito, M Seijo, GA Keller, J Somoza, RA Diez, G Di Girolamo. Vitamin D3 seems more appropriate than D2 to sustain adequate levels of 25OHD, a pharmacokinetic approach. Eur J Clin Nutr 16: 1-6, 2015.
  45. G Drelichman, N Fernández Escobar, N. Basack, et al. Consenso para la Enfermedad de Gaucher: Grupo Argentino para el diagnóstico y tratamiento de la Enfermedad de Gaucher: Revista Argentina de Hematología 19:4-51, 2015.
  46. Mastaglia S, Aguilar G, Oliveri B: Teriparatide for the rapid resolution of delayed healing of atypical fractures associated with long-term bisphosphonate use. Eur J Rheum 3: 87-90, 2016.
  47. Mautalen C, Schianchi A, Sigal A, Sigal D, Gianetti, Vidan V, Bagur A, Gonzalez D, Mastaglia S, Oliveri B. Prevalence of osteoporosis in women in Buenos Aires based on Bone Mineral Density at the lumbar Spine and Fémur. J Clin Dens 2016.
  48. Sánchez A, Brun LR, Salerni H, Constanzo P, González D, Bagur A, Oliveri B, Zanchetta MB, Farías V, Maffei L, Premrou V, Mansur JL, Larroude MS, Sarli MA, Rey P, Ulla MR, Pavlova MM, Karsbrum S, Brance ML. Grupo Argentino de Estudio de Oteoporosis: Effect of Denosumab on Bone Mineral Density and markers of Bone turnover among postmenopausal women with osteoporosis. Journal of Osteoporosis 2016 :1-6.
  49. C Fernández, B Oliveri, A Bagur, D Gómez Glorioso, D González, S Mastaglia, C Mautalen. High Prevalence of Sarcopenia in Women with Osteoporotic Fractures. J Osteopor Phys Act 2016, 4:3.
  50. Brito G, Lopez L, Oliveri B. Nutrientes y parámetros bioquímicos relacionados con la salud ósea en mujeres mayores de 65 años. Acta Bioq Latinoamericana 50: 395-406, 2016.
  51. Mastaglia S, Watson D, Bello N, Fridman V, Stecher D, Oliveri B. Vitamin D levels in HIV infected patients and their relation with mineral metabolism. Clin cases in Miner Bone Metab 14:14-18, 2017.
  52. TM Keaveny, DB Crittenden, MA Bolognese, HK Genant, K Engelke,  B Oliveri,  JP Brown, BL Langdahl,  C Yan,  A Grauer,  and C Libanati.  Greater Gains in Spine and Hip Strength for Romosozumab Compared to Teriparatide in Postmenopausal Women With Low Bone Mass. J Bone Min Res 2017
  53. Sánchez A, Brun LR, Salerni H, Costanzo P, Maffei L, Premrou V, Sarli MA,Rey P, Larroudé MS, Brance ML, Galich AM, González D, Bagur A, Oliveri B, Vega E, Zanchetta MB, Farías V, Mansur JL, Moggia MS, Ulla MR, Pavlove MM, Karlsbrum S. Evaluación de la respuesta densitométrica en pacientes con osteoporosis postmenopáusica tratadas con ranelato de estroncio o denosumab. Actual Osteología 13:9-16, 2017.
  54. Bondar C, Crivaro A, Ormazabal M, Oliveri B, González D, Mucci J, Rozenfeld P. In vitro osteoclastogenesis from gaucher patients´cells correlates with bone mineral density but not with chitotriosidase. Bone 103:262-269, 2017.
  55. Mastaglia S, Watson D,  Somoza J, Gianotti R, Brito G, Oliveri B. Estudio  comparativo de la absorción neta de calcio de dos formulaciones distintas de carbonato de calcio en mujeres posmenopáusicas. Actual Osteol 14:10-21, 2018.
  56. Seijo M, Oliveri B. Caso clínico: hipofosfatasia de la niñez: Seguimiento Clinico. Actual Osteol 14:36-43, 2018.
  57. A Metha, DJ Kuter, SS Salek, et al. Presenting signs and patients co-variables in gaucher Early Diagnosis Consensus(GED-C) Delphi initiative. Inter Med J 49:578–591, 2019.
  58. B Oliveri, D González, F Quiroga, C Silva, P Rozenfeld. A Comprehensive Study of Bone Manifestations in Adult Gaucher. Calcif Tissue Int 104: 650-657, 2019.
  59. Schurman L, Bagur A, Claus-Hermberg H, Messina OD, Negri AL, Sánchez A, González C, Diehl M, Rey P, Gamba J, Chiarpenello J, Moggia MS, Mastaglia S. Guidelines for the diagnosis prevention and treatment of osteoporosis 2012. Medicina (B Aires) 2013; 73:55-74.
  60. Mastaglia SR,  Mautalen C. Regression of an ossifying fibroma of the tibia after a fracture involving the lession. Possible role of the periostina. Clinical Cases in Mineral and Bone Metabolism 2015; 12:262-4.
  61. Mastaglia S. Effect of Time of Administration of Teriparatide on Bone Mineral Density in Glucocorticoid-Induced Osteoporosis. J Clin Densitom 2017; 20:513-515.
  62. Mastaglia S, Bagur A, Mautalen C. Underdiagnosis of osteoporosis in different ethnic groups when bone mineral density is measured in a single area. Clinical Cases in Mineral and Bone Metabolism. 2018; 15:327-333.

Mautalen Salud e Investigación

  1. Mastaglia SR, Watman NP, Oliveri B. Intravenous Bisphosphonate Treatment and Pregnancy: Its Effects on Mother and Infant Bone Health. Osteoporosis Int 2010; 21:1959-62
  2. Wittich A, Bagur A, Mautalen C, Cristofari A, Escobar O, Carrizo G, Oliveri B. Epidemiology of hip fracture in Tucumán, Argentina. Osteoporos Int 2010;21:1803-1807
  3. Mastaglia SR, Seijo M, Muzio D, Somoza J, Núñez M, Oliveri B. Effect of Vitamin D Nutritonal Status on Muscle Function and Strength in Healthy Women Aged over Sixty-Five Years. The Journal of Nutrition, Health & Aging 2011; 15:349-354.
  4. Mastaglia SR, Bagur A. Morfometria vertebral (VFA): utilidad clínica de la evaluación de las fracturas vertebrales por absorciometria de rayos-x. Actual Osteol 2011; 7(2):71-78.
  5. Seijo M, Mastaglia SR, Brito G, Somoza J, Oliveri B. ¿Es Equivalente la Suplementación Diaria con Vitamina D2 o D3 en Adultos Mayores? Revista Medicina (Buenos Aires) 2012; 72:195-200
  6. Austin M, Yang Y, Vittinghoff E, et al. Relationship between Bone Mineral Density Changes with Denosumab treatment and risk reduction for vertebral and Nonvertebral Fractures. J Bone Mineral Res. 2012, 27:687-693
  7. Mastaglia S, Solís F, Bagur A, Mautalen C, Oliveri B. Increase in android fat mass with age in healthy women with normal body mass index. J Clin Densitom 2012; 15: 159-164
  8. Schurman L, Bagur A, Claus-Hermberg H, Messina OD, Negri AL, Sanchez A, Gonzalez C, Diehl M, Rey P, Gamba J, Chiarpenello J, Moggia MS, Mastaglia S. Guidelines for the diagnosis, prevention and treatment of osteoporosis. Medicina (Buenos Aires) 2013; 73(1):55-74
  9. Schurman L, Bagur A, Claus-Hermberg H, Messina OD, Negri AL, Sanchez A, Gonzalez C, Diehl M, Rey P, Gamba J, Chiarpenello J, Moggia MS, Mastaglia S. Guías 2012 para el diagnóstico, la prevención y el tratamiento de la osteoporosis Actual Osteol 2013; 9(2):123-153
  10. Brito GM, Mastaglia SR, Goedelman C, Seijo M, Somoza J, Oliveri B. Estudio exploratorio de la ingesta y prevalencia de deficiencia de vitamina D en mujeres ³65 años que viven en su hogar familiar o en residencia para autoválidos de la ciudad de Buenos Aires, Argentina. Nutrición Hospitalaria 2013; 28 (3):816-822.
  11. Mastaglia S, Somoza J, González D, Oliveri B. Osteomalacia Tumoral. Actual Osteol 2013; 9:194-202
  12. Sánchez A, Oliveri B, Mansur J.L., Fradinger E. Guía Práctica de la Federación Argentina de Sociedades de Endocrinología. Diagnóstico, Prevención y Tratamiento de la Hipovitaminosis D. Rev Arg Endocrinol Metab 2013; 50: 140-156
  13. Mastaglia SR, Watson DZ, Oliveri B. Controversia sobre los niveles de vitamina D para la salud ósea propuestos por el Instituto de Medicina de Estados Unidos y la Comunidad Médica Internacional. Actual Osteol 2013; 9: 207-216
  14. González D. Hipofosfatemia, Recursos terapéuticos actuales. Actual Osteol 2013; 9:24
  15. G Drelichman, N Fernández Escobar, N Basack, et al. Enfermedad de Gaucher: un informe del Registro Internacional de Gaucher y Grupo Argentino de Diagnóstico y Tratamiento de la Enfermedad de Gaucher. Hematología 2013; 17(1):4-16
  16. Mastaglia S; Mautalen C. Sarcopenia: Enfoque Clínico. Actual Osteol 2014; 10:136-151
  17. González D. Densitometría ósea por DXA: sobrevida asegurada. Actual Osteol 2014; 10(1):7-10
  18. G Drelichman, N Fernández Escobar, N Basack, et al. Consenso para la Enfermedad de Gaucher: Grupo Argentino para el diagnóstico y tratamiento de la Enfermedad de Gaucher: Revista Argentina de Hematología 2015; 19:4-51
  19. Oliveri B, Mastaglia S, Brito GS, Seijo M, Keller GA, Somoza J, Diez RA, DiGirolamo G. Vitamin D3 seems more appropriate than D2 to sustain adequate levels of 25OHD, a pharmacokinetic approach. Eur J Clin Nut 2015, 69:697-702
  20. Mastaglia SR, Aguilar G, Oliveri B. Teriparatide for Rapid Resolution of Delayed Healing of Atypical Fracture Associated with Long- Term Bisphosphonate Used. Eur J Rheum 3: 87-90, 2016
  21. Mastaglia SR, Mautalen C. Regression of an ossifying fibroma of the tibia after a fracture involving the lesion. Possible role of the periostina. Clinical Cases in Mineral and Bone Metabolism. 2015; 12:262-264
  22. Brance ML, Brun LR, Lioi S, Sanchez A, Abdala M, Oliveri B.Vitamin D levels and bone mass in rheumatoid arthritis. Rheumatol Int 2015; 35:499–505
  23. Jercovich F, Moncet D,Babini S, Zoppi JA, Graciolli F, Oliveri B. Osteomalacia Oncogénica. Presentación de dos casos. Medicina (Buenos Aires) 2015; 75:37-40
  24. Bagur A, Mastaglia S, Oliveri B, Gonzalez D, Sarnacki E, Fernández C, Mautalen C. Baja masa ósea idiopática y osteoporosis secundaria en mujeres premenopáusicas. Actual Osteol 2015; 11(1):12-18
  25. Sanchez A, Brun LR, Salerni H, Costanzo PR, González D, Bagur A, Oliveri B, Zanchetta MB, Farías V, Maffei L, Premrou P, Mansur JL, Larroudé M, Sarli MA, Rey P, Ulla MR, Pavlove MM, Karlsbrum S, Brance ML. Effect of Denosumab on Bone Mineral Density and Markers of Bone Turnover among Postmenopausal Women with Osteoporosis. Journal of Osteoporosis 2016:1-6
  26. Fernández C, Oliveri B, Bagur A, Gómez Glorioso D, González D, Mastaglia S, Mautalen C. High Prevalence of Sarcopenia in Women with Osteoporotic Fractures. J Osteopor Phys Act 2016, 4:3
  27. Brito G, Lopez L, Oliveri B. Nutrientes y parámetros bioquímicos relacionados con la salud ósea en mujeres mayores de 65 años. Acta Bioq Latinoamericana 2016; 50: 395-406
  28. Zeni S, Oliveri B. Hipovitaminosis D y Sindrome Metabólico. Acta Bioq Latinoamericana 2016; 50:387-393
  29. Mautalen C, Schianchi A, Sigal A, Sigal D, Gianetti G, Vidan V, Bagur A, Gonzalez D, Mastaglia S, Oliveri B: Prevalence of osteoporosis in women in Buenos Aires based on Bone Mineral Density at the lumbar Spine and Fémur. J Clin Dens 2016.
  30. Oliveri B. Influencia de las variaciones genéticas en los niveles de 25-hidroxivitamina D. Editorial. Actual Osteol 2016; 12:75-77
  31. Mastaglia S, Bagur A, Mautalen C. Prevalencia de Osteoporosis: discrepancia de acuerdo a las áreas esqueléticas de medición. Actual Osteol 2016;12(3):162-168
  32. Mastaglia S. Osteosarcopenia: un factor de riesgo para fracturas osteoporóticas. Acta Bioquímica Clínica Latinoamericana. 2016; 50: 357-365.
  33. Mastaglia S. Periostina: su expresión en los procesos de reparación ósea. Acta Bioquímica Clínica Latinoamericana. 2016; 50: 367-373.
  34. Seijo M, Oliveri B, Deferrari JM, Casco C, Zeni SN. Marcadores de formación y resorción ósea y su utilidad para determinar el final del periodo de aposición ósea. Actual Osteol 2017; 13:28-36
  35. Mastaglia S, Watson DZ, Bello N, Fridman V, Stecher D, Oliveri B. Vitamin D levels and their impact in mineral metabolism in HIV infected patients: An exploratory study. Clinical Cases in Mineral and Bone Metabolism. 2017; 14:18:22.
  36. Mastaglia S. Effect of Time of Administration of Teriparatide on Bone Mineral Density in Glucocorticoid-Induced Osteoporosis. J Clin Densitom. 2017; 20: 513-515
  37. TM Keaveny, DB Crittenden, MA Bolognese, HK Genant, K Engelke,  B Oliveri,  JP Brown, BL Langdahl,  C Yan,  A Grauer,  and C Libanati.  Greater Gains in Spine and Hip Strength for Romosozumab Compared to Teriparatide in Postmenopausal Women With Low Bone Mass. J Bone Min Res 2017, 32:1956-1962,
  38. Bagur A. Baja masa ósea, osteoporosis primaria y secundaria en mujeres premenopáusicas. Acta Bioquim Clin Latinoam 2017;51(2):221-226
  39. Sánchez A, Brun LR, Salerni H, Costanzo P, Maffei L, Premrou V, Sarli MA,Rey P, Larroudé MS, Brance ML, Galich AM, González D, Bagur A, Oliveri B, Vega E, Zanchetta MB, Farías V, Mansur JL, Moggia MS, Ulla MR, Pavlove MM, Karlsbrum S. Evaluación de la respuesta densitométrica en pacientes con osteoporosis postmenopáusica tratadas con ranelato de estroncio o denosumab. Actual Osteol 2017; 13: 9-16
  40. Bondar C, Crivaro A, Ormazabal M, Oliveri B, González D, Mucci J, Rozenfeld P. In vitro osteoclastogenesis from gaucher patients´cells correlates with bone mineral density but not with chitotriosidase. Bone 2017; 103:262-269
  41. Schurman L, Galich AM, González C, González D, Messina OD, Sedlinsky C, Uña C, Sánchez A. Guías Argentinas para el diagnóstico, la prevención y el tratamiento de la osteoporosis 2015. Medicina (Buenos Aires) 2017; 77:46-60
  42. Kendler DL, Marin F, Zerbini CAF, Russo LA, Greenspan SL, Bagur A, Malouf-Sierra J, Lakatos P, Fahrleitner-Pammer A, Lespessailles E, Minisola S, Body JJ, Geusens P, Möricke R, López-Romero P. Effects of teriparatide and risedronate no new fractures in post-menopausal women with severe osteoporosis (VERO): a multicenter, double blind, double dummy, randomized controlled trial. Lancet 2018, 391:230-240
  43. Geusens P, Marin F, Kendler DL, Russo LA, Zerbini CAF, Minisola S, Body JJ, Lespessailles E, Greenspan SL, Bagur A, Stepan JJ, Lakatos P, Casado E, Moericke R, López-Romero P, Fahrleitner-Pammer A. Effects of Teriparatide compared with risedronate on the risk of fractures in subgroups of postmenopausal women with severe osteoporosis: The VERO Trial. J Bone Miner Res 2018; 33:1-12
  44. Seijo M, Oliveri B. Caso clínico: hipofosfatasia de la niñez: Seguimiento Clínico. Actual Osteol – 2018; 14; 36-43
  45. Mastaglia S, Watson D, Somoza J, Gianotti R, Brito G, Oliveri B. Estudio  comparativo de la absorción neta de calcio de dos formulaciones distintas de carbonato de calcio en mujeres posmenopáusicas. Actual Osteol 2018; 14:10-21
  46. Mastaglia S. Distrofia ósea esclerosante múltiple. Actual Osteol 2018; 14(2): 148-150.
  47. Metha A, Kuter DJ, Salek SS, et al. Presenting signs and patients co-variables in gaucher Early Diagnosis Consensus(GED-C) Delphi initiative. Inter Med J 2019; 49:578–591
  48. Oliveri B, González D, Quiroga F, Silva C, Rozenfeld P. A Comprehensive Study of Bone Manifestations in Adult Gaucher Disease Type 1 Patients in Argentina. Calcif Tissue Int 2019; 104: 650-657
  49. Minisola S, Marin F, Kendler DL, Geusens P, Zerbini CAF, Russo LA, Casda E, Fahrleitner-Pammer A, Stepan JJ, Lespessailles E, Moerickle R, Bagur A, Lakatos P, López-Romero P, Body JJ. Serum 25-hydroxy-vitamin D and the risk of fractures in the teriparatide versus risedronate VERO clinical trial. Arch Osteoporos 2019; 18, 14(1):10
  50. Oliveri B, Gonzalez D, Ferrari E. Bone symptoms can be an early manifestation of Gaucher disease implications for diagnosis, Endocrine and Metabolic Science 2020.

Reumatología y Enfermedades Óseas Rosario

  1. Brance ML, Pons-Estel BA, Quagliato NJ, Jorfen M, Berbotto G, Cortese N, Raggio JC, Palatnik M, Chavero I, Soldano J, Dieguez C, Sánchez A, Del Rio L, Di Gregorio S, Brun LR. Trabecular and cortical bone involvement in rheumatoid arthritis by DXA and DXA-based 3D modelling. Osteporosis Int, en prensa 2020.
  2. Brance ML, Brun LR, Cóccaro NM, Aravena A, Duan S, Mumm S, Whyte MP. High Bone Mass From Mutation Of Low-Density Lipoprotein Receptor-Related Protein 6 (LRP6). Bone. En prensa 2020.
  3. Brance ML, Di Gregorio S, Pons-Estel BA, Quagliato NJ, Jorfen M, Berbotto G, Cortese N, Raggio JC, Palatnik M, Chavero I, Soldano J, Wong R, Del Rio L, Sánchez A, Brun LR. Prevalence of sarcopenia and whole-body composition in rheumatoid arthritis. J Clin Rheumatol. En prensa 2020.
  4. Brance ML. A severe bone manifestation by primary hyperparathyroidism. Multiple brown bone tumors as a non-common presentation. Clinical Cases in Mineral and Bone Metabolism. En prensa 2019
  5. Ramírez Stieben LA, Brance ML. Mechanisms Involved in the Bone Fragility in Diabetes Mellitus. Actual. Osteol. 2018; 14(3)
  6. Brance ML. Rapid Response to golimumab in refractory adult-onset Still´s disease: A case report and review of the literature. Rev Colomb Reumatol. 2018
  7. Brance ML, Miljevic J, Tizziani R, et al. Serum 25-hydroxyvitamin D Levels in Hospitalized Adults with Community-Acquired Pneumonia. Clin Respir J. 2018; 12(7):2220-2227.
  8. Brance ML. Neffen EL. Oral mucosa lesions as atypical manifestation in adult onset Still´s disease: A case report. Reporte de Caso Clínico. An Bras Dermatol. 2018; 93(2):271-273.
  9. Ramirez Stieben LA, Brance ML, Dobry R, Anca L, González A, López MI, Bayo S, Pustilnik E, Sánchez A, Brun LR. Niveles de 25(OH)-vitamina D en pacientes con diabetes mellitus tipo 2 con y sin síndrome metabólico. Osteol 2017; 13(3): 214-222
  10. Two Cases of Gorham-Stout Disease with Good Response to Zoledronic Acid Treatment. Brance ML, Castiglioni A, Palatnik M. Clinical Cases in Mineral and Bone Metabolism. Clin Cases Miner Bone Metab. 2017;14(2):250-253.
  11. Brance ML, Larroudé MS. Masa ósea y fracturas en enfermedades reumatológicas autoinmunes. Rev Arg Reumatol. 2017; 28(1):25-33.
  12. Sánchez A, Brun LR, Salerni H, Costanzo PR, Maffei L, Premrou V, Sarli MA, Rey P, Larroudé MS, Brance ML, Galich AM, González D, Bagur A, Oliveri B, Vega E, Zanchetta MB, Farías V, Mansur JL, Moggia MS, Ulla MR, Pavlove MM, Karlsbrum S. Evaluación de la respuesta densitométrica en pacientes con osteoporosis postmenopáusica tratadas con ranelato de estroncio o denosumab. Actual. Osteol 2017;13(1):9-16.
  13. Mauro FL, Pugliese LJ, Brance ML, Guelman R; Plantalech L, Di Carlo, MB. El laboratorio bioquímico en los desórdenes óseos esclerosantes: Creatinquinasa y osteopetrosis. B y PC. 2017;81(3):15-20.
  14. Sánchez A, Brun LR, Salerni H, et al. Effect of denosumab on bone mineral density and markers of bone turnover among postmenopausal women with osteoporosis. J Osteoporos 2016;2016:8738959.
  15. Brun LR, Brance ML, Lombarte M, Maher MC, Di Loreto VE, Rigalli A. Effects of Yerba Mate (IIex paraguariensis) on Histomorphometry, Biomechanics, and Densitometry on Bones in the Rat. Calcif Tissue Int. 2015;97(5):527-34.
  16. Castiglione A, Singerman L, Brance ML. Osteonecrosis no traumática de cabeza femoral: patogénesis, diagnóstico y tratamientos actuales. Actual. Osteol 2015;11(1):57-70.
  17. Brance ML, Boscaffior A, Rodriguez ML, Miljevic J. Carcinoma de paratiroides. Descripción de un caso clínico. Actual. Osteol 2015;11(1):82-89.
  18. Brance ML, Brun LR, Lioi S, Sánchez A, Abdala M, Oliveri B. Vitamin D levels and bone mass in rheumatoid arthritis. Rheumatol Int. 2015;35(3):499-505.
  19. Lupo M, Brance ML, Fina BL, Brun LR, Rigalli A. Methodology developed for the simultaneous measurement of bone formation and bone resorption in rats based on the pharmacokinetics of fluoride. J Bone Miner Metab. 2015;33(1):16-22.
  20. Brun LR, Galich AM, Vega E, Salerni H, Maffei L, Premrou V, Costanzo PR, Sarli MA, Rey P, Larroudé MS, Moggia MS, Brance ML, Sánchez A. Strontium ranelate effect on bone mineral density is modified by previous bisphosphonate treatment. Springerplus. 2014;18(3):676
  21. Lombarte M, Brun LR, Brance ML, Bues F, Di Loreto VE. Efecto diferencial del ácido zoledrónico sobre el hueso trabecular y cortical de ratas ovariectomizadas. Actual. Osteol 2014;10(2):175-176.
  22. Brance ML, Brun LR, Di Loreto VE, Lupo M, Rigalli A. Sequential treatment with monofluorophosphate and zoledronic acid in osteoporotic rats. Climacteric. 2014;17(4):478-85.
  23. Brance ML, Plantalech L. Osteoporosis inducida por glucocorticoides: análisis de las guías internacionales de prevención y tratamiento. Actual Osteol 2013; 9(1): 14-27.
  24. Brance ML, Abdala M. Osteoporosis en Artritis Reumatoidea: patogénesis y repercusión en el metabolismo óseo. AR Artritis Reumatoidea.2010;1(1):1-7.

Sección Osteopatías Metabólicas HIBA

  1. Morán VM, Diehl M, Plantalech LC. Servicio de enlace para pacientes con fracturas por osteoporosis. Osteol 2019; 15(1):44-56
  2. Buttazzoni M, Galich AM. Fracturas vertebrales múltiples postsuspensión de denosumab. Revisión del tema a partir de dos casos clínicos. Actual Osteol 2019; 15(1): 57-64.
  3. Collaud C, Musumeci M, Mollerach A, Arma I, Hume I, Cianciarelli C, Vázquez E, Galich AM, Diehl M, Guelman R, Kitaidgrosky A, Buttazzoni M, Biedak P, Schonfeld M, Figari M, Jager V. Utilidad del 18F-Colina PET/TC en hiperparatiroidismo primario persistente o recurrente. Actual. Osteol 2019; 15(1): 11-19.
  4. Boccalatte LA, Felipe Higuera F,  Gómez NL, Yanzon A, Mazzarro E, Galich AM, Collaud C; Figari MF. Utilidad de la tomografía por emisión de positrones con 18 F-fluorocolina en la localización de lesiones en el hiperparatiroidismo. Una revisión sistemática. Otolaryngol Head Neck Surg. 2019; 145 (8): 743-750. 
  5. Bosco MB,  Diehl M,  Galich AM, Jager V, Massaro E, Plantalech L. Hipercalcemia hipocalciúrica familiar en una paciente con mutación del receptor de calcio: forma atípica de presentación y tratamiento con cinacalcet.  Actual. Osteol 13(1):69-79, 2017 
  6. Trasante Borches MS, Giovenco MB, Bernard NE, Diehl M, Zanotti G, Russo P, Andresik D. Calcificaciones heterotópicas en paciente politraumatizado. Revista del Hospital Italiano de Buenos Aires, 2017, (37):1.
  7. Galich AM, Maffei L, Premrou V, Frigeri A, Vega E. Evaluación del score de hueso trabecular (TBS) en pacientes menopáusicas con fracturas y sin ellas. Actual Osteol 2017; 13(2):96-103.
  8. Schurman L, Galich AM, Gonzalez C, Gonzalez D, Messina O, Sedlinsky C, Uña CR, Sánchez A. Guías argentinas para el diagnóstico, la prevención y el tratamiento de la osteoporosis 2015. Medicina (Buenos Aires) 2017; 77: 46-60.
  9. Diehl M. Osteosclerosis asociada a mastocitosis sistémica. Acta Bioquím Clín Latinoam 2016; (50)3: 429-434.
  10. Serra MM, Morgunovsky M, Rojas,SL Diehl M, Elizondo MC. Hypophosphatemia induced by intravenous administration of iron in patients with hereditary hemorrhagic telangiectasia. A new clinical issue?. Angiogenesis 2015; 18(4):566-566
  11. Kitaigrodsky A, Diehl M, Galich AM, Lovazzano S, Santangelo L, Giunta D, Plantalech L. Tratamiento prolongado con teriparatida en el hipoparatiroidismo grave de difícil manejo. Osteol 2015; 11(2): 114-124 
  12. Plantalech L. ¿Existen métodos y tratamientos eficaces para la prevención de fracturas de cadera y otras mayores? Actual. Osteol 2015; 11 (3): 227
  13. Crucelegui MS, Rosa Diez G, Serra M, Ortíz MI, Diehl M. Síndrome de hueso hambriento asociado al hiperparatiroidismo secundario a enfermedad renal crónica. Actual. Osteol 2014; 10(1): 11-19.
  14. Figari M, Musso CG, Plantalech L, Lambertini R, Rivera H, Mollerach A. Local ethanol injection for the treatment of deltoid parathyroid cell hyperplasia. Int Urol Nephrol 2014; 46(1):247-9
  15. Rosa Diez G, Crucelegui MS, Bratti GI, Diehl M, Galich A. Diagnóstico de calcificaciones vasculares. Actual. Osteol 2014; 10(1):82-84.
  16. Diehl M, Carrizo MC, Fantl D, Jiménez GB. Hipofosfatemia e hiperfosfatemia espurias en una paciente con mieloma múltiple. Actual Osteol 2014; 10(1): 91-96.
  17. Diehl M, Beratarrechea A, Saimovici J, Pace N, Trossero A, Giardini G, Perman G. Niveles de vitamina D en pacientes con fractura de cadera. Actual. Osteol 2014; 10(3):254-263.
  18. Negri AL, Rosa Diez G, Del Valle E, Piulats E, Greloni G, Quevedo A, Varela F, Diehl M, Bevione P. Hypercalcemia secondary to granulomatous disease caused by the injection of methacrylate: a case series. Clin Cases Miner Bone Metab. 2014;11(1):44-8
  19. Brun LR, Galich AM, Vega E, et al. Strontium ranelate effects on bone mineral density is modified by previous bisphosphonate treatment. Springer Plus 2014; 3:676.
  20. Alonso G, Plantalech L, Guelman R, González s, Cassinelli H, Redal M, Pasqualini T. Raquitismo hipofosfatémico familiar y esporádico: clínica y hallazgos moleculares. Actual. Osteol 2014; 10(2):192-205.
  21. Schurman L, Bagur A, Claus-Hermberg H, Messina OD, Negri AL, Sánchez A, González C, Diehl M, Rey P, Gamba J, Chiarpenllo J, Moggia MS, Mastaglia S. Guidelines for the diagnosis, prevention and treatment of osteoporosis 2012. Medicina (B Aires) 2013; 73(1):55-74.
  22. Diehl M, Beratarrechea A, Pace N, Saimovici J, Trossero A, Perman G, Plantalech L. Disminución del riesgo de mortalidad en pacientes tratados con bifosfonatos luego de una fractura de cadera por osteoporosis. Actual Osteol 2013; 9(2):154-164.
  23. Diehl M, Morandi A, Plantalech L. Mastocitosis sistémica. Actual. Osteol 2013; 9(3):288-289.
  24. Brance ML, Plantalech L. Osteoporosis inducida por glucocorticoides: análisis de las guías internacionales sobre prevención y tratamiento. Actual Osteol 2013; 9(1):14-24
  25. Ferreyra-Garrot, L, Meneses G, Plantalech L. Osteólisis multicéntrica no hereditaria con nefropatía: reporte de un caso y revisión de la literatura. Osteol 2013; 9(2):217-224
  26. Carrizo C, Vidal G, Plantalech L. Osteoporosis inducida por corticoides: prevalencia del tratamiento preventivo en la población de un sistema cerrado de salud. Actual Osteol 2013; 9(3):268-276.
  27. Plantalech L. Osteogénesis Imperfecta tipo V y tumor en pie izquierdo. Actual Osteol 2013; 9 (3): 292-293.
  28. Buttazzoni M Carabelli G, Diehl M. Fractura atípica en paciente con tratamiento prolongado con bifosfonatos. Revista del Hospital Italiano de Buenos Aires, 2012; 32(4):182-4.
  29. Diehl M et al. Programa de prevención secundaria en pacientes con fractura de cadera. Hospital Italiano de Buenos Aires, 2011; 31(4):131-6
  30. Beratarrechea A, Diehl M, Saimovici J, Pace N, Trossero A, Plantalech L. Mortalidad a largo plazo y factores predictores en pacientes con fractura de cadera. Actual. Osteol 7(1): 9-18 2011
  31. Galich AM. Ranelato de estroncio. Tratamiento para osteoporosis. Actual Osteol. 2011; 7(1):19-34.
  32. Gleran M, Furci A, Galich AM, Fama B and Plantalech L. Bone and mineral metabolism in primiparous women and its relationship with breastfeeding: a longitudinal study. Medicina (Buenos Aires): 70: 227-232, 2010.

Servicio de Endocrinología y Densitometría ósea. Hospital Alemán

  1. Claus-Hermberg H, Lozano MP, Rey M, Pozzo MJ. Importancia relativa de las modificaciones del contenido mineral óseo y del área en la determinación del descenso de la densidad mineral ósea del cuello femoral en la posmenopausia. Actual Osteol 6(1):9:15, 2010.
  2. Claus-Hermberg H, Lozano MP, Rey M, Martínez MP, Pozzo MJ. Modificaciones densitométricas, geométricas y de redistribución de la masa ósea del cuello femoral asociadas a la edad evaluadas por DXA. Actual Osteol 2012; 8(2): 72-78.
  3. Schurman L, Bagur A, Claus-Hemberg H, Messina O, Negri H, Sanchez A, Gonzalez C, Diehl M, Rey P, Gamba J, Moggia MS, Mastaglia S. Guías 2012 para el diagnóstico, la prevención y el tratamiento de la osteoporosis Medicina (Buenos Aires) 2013; 73: 55-74.
  4. Claus Hermberg H, Pozzo MJ. Controversias: Fracturas atípicas asociadas al uso prolongado de bifosfonatos: ¿un problema menor? Actual Osteol 9(1):86-95, 2013.
  5. Rey M, Lozano MP, Martínez MP, Bomarito MP, Pozzo MP, Casas G, Canalis M. Hipercalcemia asociada a granuloma por cuerpo extraño en paciente con HIV. Actual. Osteol 2013; 9(1): 96-101.
  6. Pozzo MJ. Controversias: Uso de marcadores de remodelación ósea en la práctica clínica. Actual. Osteol 2014; 10(2):177-185.
  7. Pozzo MJ. Editorial. Hipercalcemia causada por granulomas inducidos por inyección de metacrilato: una nueva entidad de gravedad insospechada. Actual. Osteol 2014; 10(3): 234-237
  8. Claus- Hermberg H, Pozzo MJ. Controversias. Una visión a favor de la postura de Järvine en relación a la prevención de fracturas osteoporóticas. Actual Osteol 11(3):233:238, 2015.
  9. Claus- Hermberg H, Pozzo MJ. Actualizaciones: Aspectos clínicos de las fracturas por stress. Actual. Osteol 2016; 12(1):47-56
  10. Claus Hermberg H, De Luca S, Troncoso F, Lozano MP;  Rey M,  Boffa S,  Pozzo MJ.  Densidad ósea volumétrica vertebral obtenida sin fantoma en estudios de rutina de tomografía computarizada de abdomen: correlación con los valores medidos por densitometría ósea areal por rayos x. Actual Osteol 2016; 12(3):180-187.
  11. Claus Hermberg H. Editorial. Score óseo trabecular (TBS): una herramienta derivada de DMO DXA destinada a mejorar la predicción de fracturas osteoporóticas en mujeres menopáusicas. Actual. Osteol 13(2):92:95, 2017.
  12. Claus-Hermberg H, Lozano MP, Rey M, Boffa S, Pozzo MP Las diferencias antropométricas entre sexos de la columna lumbar, medidas por DXA, no afectan a todas las vértebras en forma uniforme: probable implicancia en la incidencia de fracturas.  Actual Osteol 14(3):185:190, 2018.